Suggested Level of Knowlege: Detailed

LOs

Pharmacodynamics

BT_GS 1.31 Describe and compare the pharmacodynamics of intravenous induction and sedative agents and in particular the effects on the cardiovascular, respiratory and central nervous systems

BT_AM 1.3 Describe the effect of anaesthetic agents and other drugs on airway reflexes

BT_GS 1.48 Describe the effects of anaesthetic agents on regional circulation

Past SAQs

2016.1 Describe the pharmacodynamic properties of propofol EXCLUDING its effects on the central nervous system. Describe how these influence clinical use.

2006.1 Describe the pharmacodynamic properties of propofol and how this influences its clinical usage.

2003.2, 2001.1 Outline GABA's role as a neuro transmitter and indicate how its actions may be modified by pharmacological agents.

2003.1,1999.1 Outline the neuropharmacology of thiopentone, covering only its site of action, EEG changes, effects on cerebral blood flow and intracranial pressure.

2000.2 Write short notes contrasting the cardiovascular effects of propofol and ketamine seen clinically.

2002.1 Briefly outline the effects of thiopentone and ketamine not mediated via the central nervous system.

1999.2 Briefly outline the effects of intravenous induction agents not mediated via the central nervous system.

IV Agent Pharmacodynamics