Suggested Level of Knowlege: Detailed

LOs

BT_GS 1.29 Describe the physical properties of sedative/hypnotic agents, including:

· Formulation

· Properties of an ideal agent

· Structure-activity relationships

Past SAQs

2008.1 Describe the ideal pharmacokinetic and pharmacodynamic properties of agents used for sedation. Outline the pharmacology of midazolam and propofol with reference to these ideal properties.

2001.1 Outline the NON-ideal features as an intravenous induction agent of the current formulations of propofol.

IV Agent Physical Properties Formulation & SARs