Suggested Level of Knowlege: Detailed

LOs

BT_GS 1.59 Describe the pharmacological principles of and sources of error with target controlled infusion

Past SAQs

2016.2, 2010.2 Describe the principles of how a computer-controlled infusion device targets and maintains a constant effect-site concentration of propofol.

2008.2 Describe the pharmacokinetic principles of total intravenous anaesthesia using propofol.

2003.2 Describe how a computer-controlled infusion device targets and maintains constant blood concentrations of propofol.

References

Propofol TCI is a little sketchy in the texts. A good article is:

Absalom. Pharmacokinetic models for propofol—defining and illuminating the devil in the detail. BJA 2009 103(1):26-37

Target Controlled Infusions