Suggested Level of Knowlege: Detailed
LOs
IT_GS 1.1 Outline the basic pharmacology of sedative/hypnotic agents (propofol, thiopentone, midazolam, ketamine), inhalational agents, opioids, muscle relaxants, reversal drugs and anti- emetic agents relevant to their clinical practice.
BT_GS 1.27 Describe the pharmacology of nitrous oxide
BT_GS 1.28 Describe the comparative pharmacology of nitrous oxide, halothane, enflurane, isoflurane, desflurane, sevoflurane, xenon and ether
BT_PM 1.9 Describe the pharmacology of the following agents applicable to pain management, including:
· Opioids
· Tramadol
· Local anaesthetic agents (also refer to the Regional and local anaesthesia clinical fundamental)
· NSAIDs
· Paracetamol
· NMDA antagonists
· Anticonvulsants
· Antidepressants
· Corticosteroids
· Inhalational analgesics - nitrous oxide, methoxyflurane
BT_GS 1.57 Explain the techniques of intravenous and inhalational induction and describe clinical indications and advantages and disadvantages of both techniques
Past SAQs
2017.1, 2011.1 Describe the advantages and disadvantages of using nitrous oxide as part of a general anaesthetic.
2015.1, 2013.1, 2009.2 Sevoflurane and fentanyl are a common anaesthetic drug combination. Discuss pharmacological reasons why it is useful to use them together.
2013.1 What are the advantages and disadvantages of xenon as an anaesthetic agent?
2011.2 Compare and contrast the clinically significant cardiovascular and central nervous system effects of desflurane and sevoflurane
2012.2 Compare and contrast propofol and sevoflurane for maintenance of anaesthesia with respect to kinetics, cardiovascular and central nervous system effects.
2006.2 Compare and contrast the clinically significant respiratory, cardiovascular and central nervous system effects of desflurane and isoflurane.