Suggested Level of Knowlege: Detailed
LOs
BT_PM 1.10 Describe the effect of physiological change and pathological disturbance on the pharmacology of the agents listed in learning outcome BT PM 1.9 (Opioids, Tramadol, Local anaesthetic agents, NSAIDs, Paracetamol, NMDA antagonists, Anticonvulsants, Antidepressants, Corticosteroids, Inhalational analgesics - nitrous oxide,methoxyflurane), with special reference to the elderly
SS_PA 1.79 Describe the maximum safe doses of local anaesthetic agents in different age groups
SS_PA 1.78 Describe the difference in pharmacokinetics of local anaesthetic agents in neonates and children from adults and the implications for regional blockade
LA: Variability With Age, Physiology & Pathology