Suggested Level of Knowlege: Detailed

LOs

SS_OB 1.9 Describe the influence of pregnancy on the pharmacokinetics and pharmacodynamics of drugs commonly used in anaesthesia and analgesia

Past SAQs

2016.2 Describe the effect of a pregnancy, at term, on wash-in of volatile anaesthetic agents.

2007.1 After epidural injection in a health term pregnant woman, discuss the factors influencing the distribution of bupivacaine to (a) the maternal CSF

and spinal cord; (b) the maternal circulation; (c) the foetus.

2002.2 Outline the influences of pregnancy on pharmacokinetics

Drug Variability in Pregnancy