Suggested Level of Knowlege: Good

LOs

BT_PO 1.58 Describe the pharmacology of anti-hypertensive agents and their clinical application, including the following agents:

clonidine

alpha-methyl dopa

alpha and beta blockers

nitric oxide

sodium nitroprusside and

glyceryl trinitrate

calcium antagonists

ACE inhibitors and

angiotensin receptor antagonists

hydralazine and the

potassium channel activators.

Past SAQs

2012.2 Discuss the pharmacology of drugs that inhibit the activity of the renin-angiotensin system. What particular problems can occur in the anaesthetised patient taking these drugs?

2007.2 Write short notes on anti-hypertensive drugs that exert their action via blocking the effects of angiotensin.

Antihypertensives