Suggested Level of Knowlege: Good

LOs

BT_PO 1.54 Describe the pharmacology of commonly used alpha and beta receptor blocking agents, their clinical use, adverse effects and use in the perioperative period

BT_PO 1.57 Describe the pharmacology of antiarrhythmic agents and their clinical applications including the following agents: lignocaine, flecainide, beta blockers, amiodarone, sotalol, ibutilide, calcium antagonists, digoxin, adenosine, and magnesium

BT_PO 1.58 Describe the pharmacology of anti-hypertensive agents and their clinical application, including the following agents:

clonidine

alpha-methyl dopa

alpha and beta blockers

nitric oxide

sodium nitroprusside and glyceryl trinitrate

calcium antagonists

ACE inhibitors and angiotensin receptor antagonists

hydralazine and the

potassium channel activators.

SS_OB 1.12 Describe the pharmacology of agents used for the treatment of pre-eclampsia including magnesium, hydralazine and labetolol

Past SAQs

2011.2 What is the mechanism of action of β-adrenoreceptor antagonists? Outline the therapeutic uses and side effects of these drugs.

2008.1 Define the mechanisms of action and adverse effects of metoprolol, glyceryl trinitrate and diltiazem when used to manage myocardial ischaemia.

2005.2 Describe the adverse effects of beta adrenoreceptor antagonists.

2002.2, 2001.2 Outline the potential pharmacological advantages and disadvantages of intra- operative beta-blockade.

2001.1 Compare and contrast the pharmacology of esmolol and propranolol

Beta Blockers