Suggested Level of Knowlege: Detailed

LOs

BT_GS 1.35 Describe the physiology of the neuromuscular junction and the mechanism of action of neuromuscular blocking agents

BT_PO 1.98a Describe the physiology of skeletal muscle including mechanism of excitation contraction coupling and compare the physiology of skeletal muscle with that of cardiac muscle.

Past SAQs

2006.2 Briefly describe the structure of a mammalian skeletal muscle fibre and explain how its structure is related to its contractile function. DO NOT describe excitation-contraction coupling.

2004.2, 2000.1 Briefly describe the difference between a single twitch and a tetanic contraction in a skeletal muscle fibre. Include in your answer the physiological basis for the development of a tetanic contraction.

2001.1 Briefly describe the effect of resting muscle length and load conditions on the tension generated by a skeletal muscle. How do these factors affect the velocity of shortening?

2000.1 Briefly discuss the relationship between structure and function in skeletal muscle.

Muscle Physiology