Suggested Level of Knowlege: Good

LOs

BT_PO 1.110 Describe the physiological consequences of acute and chronic anaemia

BT_PO 1.111 Outline the major haemoglobinopathies and their clinical significance

BT_PO 1.112 Describe the physiology of haemostasis, including:

· Coagulation

· The role of platelets

· Fibrinolysis

BT_PO 1.113 Describe the physiological mechanisms of limiting and preventing thrombosis

BT_RT 1.7 Describe blood groups and the physiological basis of transfusion reactions

BT_RT 1.74 Outline the constituents and functions of plasma.

Past SAQs

2013.2 Briefly describe the breakdown of haemoglobin after red cell lysis.

2011.2 Outline the similarities and differences between myoglobin and adult haemoglobin, explaining the physiological relevance of the differences.

2009.2 Discuss the production and function of red blood cells

2007.1, 1999.1 Explain the mechanisms that prevent blood clotting in intact blood vessels (do not draw the clotting cascade).

2006.1 Briefly outline the role of platelets in haemostasis.

2005.2 Briefly discuss the physiological roles of plasma proteins.

2001.2 Explain the main difference between the intrinsic and extrinsic pathways of coagulation.

2000.1 Briefly describe the breakdown of haemoglobin after red cell lysis.

References

Blood Physiology